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Cell Reactant:Intestinal fatty acid-binding protein (hIFABP)
Syringe Reactant:BDBM50085041
Meas. Tech.:Enzyme Inhibition
Entry Date:10/05/15
 
ΔG°:-30.6±0.590 (kJ/mole)
pH:8±0
Log10Kb:5.15± n/a
Temperature:310.15±0 (K)
ΔH° :-42.7±6.03 (kJ/mole)
ΔHobs:n/a
Ionic Strength:n/a
Corrected for ΔHioniz:n/a
Protons Released:n/a
ΔCp :n/a
Stoich. Param.:n/a
ΔS° : -0.0393±0.0200 (kJ/mole-K)
Comments:n/a
 
Citation Patil, RLaguerre, AWielens, JHeadey, SJWilliams, MLHughes, MLMohanty, BPorter, CJScanlon, MJ Characterization of two distinct modes of drug binding to human intestinal fatty acid binding protein. ACS Chem Biol9:2526-34 (2014) [PubMed]  Article
More Info.:  Get all data from this article ,  ITC RUN data
 
Intestinal fatty acid-binding protein (hIFABP)
Source:n/a
Purity:n/a
Prep. Method:n/a
Name:Intestinal fatty acid-binding protein (hIFABP)
Synonyms:FABPI | Fatty acid binding protein intestinal | Fatty acid-binding protein, intestinal | I-FABP
Type:Protein
Mol. Mass.:15207.56
Organism:Homo sapiens (Human)
Description:n/a
Residue:132
Sequence:
MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTITQEGNKFTVKESSAFRNIE
VVFELGVTFNYNLADGTELRGTWSLEGNKLIGKFKRTDNGNELNTVREIIGDELVQTYVY
EGVEAKRIFKKD
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50085041
Source:n/a
Purity:n/a
Prep. Method:n/a
NameBDBM50085041
Synonyms:2-(4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy)phenoxy)acetic acid | CHEMBL153057 | L-165041 | L165041 | {4-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-propoxy]-phenoxy}-acetic acid(L-165041) | {4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy}acetic acid
TypeSmall organic molecule
Emp. Form.C22H26O7
Mol. Mass.402.4376
SMILESCCCc1c(O)c(ccc1OCCCOc1ccc(OCC(O)=O)cc1)C(C)=O
Structure
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