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Cell Reactant:Phospholipase C-γ1 SH2 domain (PLCC)
Syringe Reactant:BDBM225244
Meas. Tech.:Enzyme Inhibition
Entry Date:05/11/17
 
ΔG°:-46.6± (kJ/mole)
pH:7.4±0
Log10Kb:8.17± 7.52
Temperature:298.15±0 (K)
ΔH° :-10.9±1.40 (kJ/mole)
ΔHobs:n/a
Ionic Strength:n/a
Corrected for ΔHioniz:n/a
Protons Released:n/a
ΔCp :n/a
Stoich. Param.:n/a
ΔS° : 0.0641±0.00500 (kJ/mole-K)
Comments:n/a
 
Citation McKercher, MAGuan, XTan, ZWuttke, DS Multimodal Recognition of Diverse Peptides by the C-Terminal SH2 Domain of Phospholipase C-1 Protein. Biochemistry56:2225-2237 (2017) [PubMed]  Article
More Info.:  Get all data from this article ,  ITC RUN data
 
Phospholipase C-γ1 SH2 domain (PLCC)
Source:n/a
Purity:n/a
Prep. Method:n/a
Name:Phospholipase C-γ1 SH2 domain (PLCC)
Synonyms:n/a
Type:Protein
Mol. Mass.:11560.59
Organism:Homo sapiens (Human)
Description:Human phospholipase C-γ1 C-terminal SH2 domain (663-759 aa)
Residue:97
Sequence:
HESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQ
TVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM225244
Source:n/a
Purity:n/a
Prep. Method:n/a
NameBDBM225244
Synonyms:IGF1R-pep | N-(2-phenylbenzo[d]oxazol-6-yl)-4-(trifluoromethoxy)benzenesulfonamide (5)
TypeSmall organic molecule
Emp. Form.C63H88N13O26P
Mol. Mass.1474.4181
SMILESCC(C)[C@H](NC(=O)[C@@H](N)CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(O)=O |r|
Structure
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