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Target
Mu-type opioid receptor
Ligand
BDBM309420
Substrate
n/a
Meas. Tech.
δ-Opioid Receptor Binding Assay
EC50
>20000±n/a nM
Citation
 Lockman, J; Tafesse, L Ring-contracted morphinans and the use thereof US Patent  US9656962 Publication Date 5/23/2017 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM309420
Synonyms:
(2S,3aS,4R,9bS)-2-amino-12- (cyclopropylmethyl)-8-methoxy- 1,2,3,3a,4,5-hexahydro-4,9b- (epiminoethano)cyclopenta[a]naphthalene- 3a-ol | US9656962, Compound 28
Type:
Small organic molecule
Emp. Form.:
C20H28N2O2
Mol. Mass.:
328.4485
SMILES:
COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(C[C@H](N)C[C@@]34O)c2c1 |r,TLB:9:8:20:22.5.6|
Structure:
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