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TargetBRD4 BD1 (aa 42-168)
LigandBDBM310887
Substrate/Competitorn/a
Meas. Tech.BRD4 AlphaLisa Binding Assay
IC50 320±n/a nM
Citation Albrecht, BKBellon, SFBurdick, DJCote, ACrawford, TDakin, LAHsiao-Wei Tsui, VHewitt, MCLeBlanc, YMagnuson, SRNasveschuk, CGRomero, AFTang, YTaylor, AMWang, S Therapeutic compounds and uses thereof US Patent US10150767 Publication Date 12/11/2018
More Info.:Get all data from this article,  Assay Method
 
BRD4 BD1 (aa 42-168)
Name:BRD4 BD1 (aa 42-168)
Synonyms:Bromodomain-containing protein 4 Bromo Domain 1
Type:Enzyme Catalytic Domain
Mol. Mass.:15054.68
Organism:Homo sapiens (Human)
Description:n/a
Residue:127
Sequence:
STNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKII
KTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKI
NELPTEE
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BDBM310887
NameBDBM310887
Synonyms:4-[4-(4-acetylpiperazine-1-carbonyl)phenyl]-6-methyl-1H-pyrrolo[2,3-c]pyridin-7-one | US10150767, Example 32
TypeSmall organic molecule
Emp. Form.C21H23N5O3
Mol. Mass.393.439
SMILESCn1cc(-c2ccc(cc2)C(=O)N2CCN(CC(N)=O)CC2)c2cc[nH]c2c1=O
Structure
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n/a