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Target
Bromodomain-containing protein 9 [134-239]
Ligand
BDBM310895
Substrate
n/a
Meas. Tech.
BRD9 AlphaLisa Binding Assay
IC50
31.0±n/a nM
Citation
 Albrecht, BK; Bellon, SF; Burdick, DJ; Cote, A; Crawford, T; Dakin, LA; Hsiao-Wei Tsui, V; Hewitt, MC; LeBlanc, Y; Magnuson, SR; Nasveschuk, CG; Romero, AF; Tang, Y; Taylor, AM; Wang, S Therapeutic compounds and uses thereof US Patent  US10150767 Publication Date 12/11/2018 
Target
Name:
Bromodomain-containing protein 9 [134-239]
Synonyms:
BRD9 | BRD9 (aa 134-239) | BRD9_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12286.22
Organism:
Homo sapiens (Human)
Description:
Q9H8M2[134-239]
Residue:
106
Sequence:
AENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSK
  
Inhibitor
Name:
BDBM310895
Synonyms:
3-methyl-7-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one | US10150767, Example 11
Type:
Small organic molecule
Emp. Form.:
C18H18N4O2
Mol. Mass.:
322.3611
SMILES:
CC1CNc2cc(ccc2NC1=O)-c1cn(C)c(=O)c2[nH]ccc12
Structure:
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