Reaction Details Report a problem with these data
Target
Estrogen receptor beta
Ligand
BDBM25807
Substrate
n/a
Meas. Tech.
Competitive Binding Assay
IC50
32000±n/a nM
Citation
 Gallucci, RR; Mahood, JA; Odle, RR; Dimond, S Polyetherimide compositions and methods for the manufacture and use thereof US Patent  US9688816 Publication Date 6/27/2017 
Target
Name:
Estrogen receptor beta
Synonyms:
ER-beta | ESR2 | ESR2_HUMAN | ESTRB | Estradiol receptor beta (ERβ) | Estrogen receptor | Estrogen receptor (ER beta) | Estrogen receptor beta | Estrogen receptor beta (ER beta) | Estrogen receptor beta (ER) | NR3A2 | Nuclear receptor subfamily 3 group A member 2 | estrogen beta
Type:
Protein
Mol. Mass.:
59238.43
Organism:
Homo sapiens (Human)
Description:
Q92731
Residue:
530
Sequence:
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPSNVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
  
Inhibitor
Name:
BDBM25807
Synonyms:
4,4 -Dihydroxybenzophenone | 4-[(4-hydroxyphenyl)carbonyl]phenol | Bis(p-hydroxy)benzophenone | Compound 0627-0373 (DHBP) | US9688816, N
Type:
Small organic molecule
Emp. Form.:
C13H10O3
Mol. Mass.:
214.2167
SMILES:
Oc1ccc(cc1)C(=O)c1ccc(O)cc1
Structure:
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