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TargetCalcitonin gene-related peptide (CGRP alpha)
LigandBDBM311886
Substrate/Competitorn/a
Meas. Tech.Radioligand Binding Assay
Ki 0.050±n/a nM
Citation Christopher, JACongreve, MSBucknell, SJDeflorian, FPickworth, MMason, JS CGRP receptor antagonists US Patent US10166226 Publication Date 1/1/2019
More Info.:Get all data from this article,  Assay Method
 
Calcitonin gene-related peptide (CGRP alpha)
Name:Calcitonin gene-related peptide (CGRP alpha)
Synonyms:CGRP | Calcitonin gene-related peptide 1
Type:Enzyme
Mol. Mass.:13902.80
Organism:Homo sapiens (Human)
Description:P06881
Residue:128
Sequence:
MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQNYVQ
MKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFG
RRRRDLQA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM311886
NameBDBM311886
Synonyms:N-[(2R)-1-[4-(1H-imidazol-2-yl)-1,4'-bipiperidin-1'-yl]-3-(7-methyl-1H-indazol-5-yl)-1-oxopropan-2-yl]-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide | US10166226, Example 1
TypeSmall organic molecule
Emp. Form.C39H47N9O3
Mol. Mass.689.849
SMILESCc1cc(C[C@@H](NC(=O)N2CCC(CC2)c2cc3ccccc3[nH]c2=O)C(=O)N2CCC(CC2)N2CCC(CC2)c2ncc[nH]2)cc2cn[nH]c12 |r|
Structure
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