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TargetBromodomain-containing protein 2 Bromo 2 domain(BRD2 BD2)
LigandBDBM50092324
Substrate/Competitorn/a
Meas. Tech.FP Competitive Binding Assay (No.350)
Temperature298.15±n/a K
Ki 35±2.10 nM
Commentsextracted
Citation Wang, SRan, XZhao, YYang, CLiu, LBai, LMcEachern, DStuckey, JMeagher, JLSun, DLi, XZhou, BKaratas, HLuo, RChinnaiyan, AAsangani, IA BET bromodomain inhibitors and therapeutic methods using the same US Patent US9675697 Publication Date 6/13/2017
More Info.:Get all data from this article,  Assay Method
 
Bromodomain-containing protein 2 Bromo 2 domain(BRD2 BD2)
Name:Bromodomain-containing protein 2 Bromo 2 domain(BRD2 BD2)
Synonyms:n/a
Type:Protein
Mol. Mass.:8615.14
Organism:Homo sapiens (Human)
Description:BD2 (364-436 aa) of P25440
Residue:73
Sequence:
KHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFS
NCYKYNPPDHDVV
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BDBM50092324
NameBDBM50092324
Synonyms:CHEMBL3581655 | US9675697, Cpd. No. 1
TypeSmall organic molecule
Emp. Form.C22H20N4O3
Mol. Mass.388.4192
SMILESCOc1cc2c(cc1-c1c(C)noc1C)[nH]c1ccnc(-c3c(C)noc3C)c21 |(5.34,2.95,;5.34,1.67,;3.96,.87,;2.62,1.63,;1.3,.87,;1.3,-.64,;2.62,-1.4,;3.96,-.64,;5.34,-1.44,;5.49,-3.01,;4.53,-3.86,;7.04,-3.34,;7.84,-1.97,;6.77,-.78,;7.03,.46,;,-1.4,;-1.3,-.64,;-2.64,-1.4,;-3.92,-.64,;-3.92,.87,;-2.64,1.63,;-2.66,3.22,;-1.38,4.15,;-.17,3.76,;-1.89,5.66,;-3.48,5.64,;-3.96,4.12,;-5.16,3.71,;-1.3,.87,)|
Structure
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