Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50374601
Substrate
n/a
Meas. Tech.
Receptor Assay
Ki
3.37±0.28 nM
Citation
 McCurdy, CR; Mesangeau, C; Chin, FT; James, ML; Shen, B; Gambhir, S Highly selective sigma receptor radioligands US Patent  US9604926 Publication Date 3/28/2017 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Opioid receptor, sigma 1 | Oprs1 | SGMR1_MOUSE | Sigma 1-type opioid receptor | Sigma1-receptor | Sigma1R | Sigmar1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25246.51
Organism:
Mus musculus (Mouse)
Description:
O55242
Residue:
223
Sequence:
MPWAAGRRWAWITLILTIIAVLIQAAWLWLGTQNFVFSREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCILHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWKEGTTKSEVFYPGETVVHGPGEATALEWGPNTWMVEYGRGVIPSTLFFALADTFFSTQDYLTLFYTLRAYARGLRLELTTYLFGQDS
  
Inhibitor
Name:
BDBM50374601
Synonyms:
CHEMBL408003 | US9604926, Compound CM-135 | US9724435, Compound CM-135
Type:
Small organic molecule
Emp. Form.:
C21H31N3OS
Mol. Mass.:
373.555
SMILES:
C(CCN1CCN(CC1)C1CCCCC1)CSc1nc2ccccc2o1
Structure:
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