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Target
Steroid hormone receptor ERR2
Ligand
BDBM312137
Substrate
n/a
Meas. Tech.
Competitive Radioligand-Binding Assay
Ki
130±n/a nM
Citation
 Narayanan, R; Dalton, JT; Levin, E Nuclear receptor binding agents US Patent  US9604931 Publication Date 3/28/2017 
Target
Name:
Steroid hormone receptor ERR2
Synonyms:
ERR beta-2 | ERR-beta | ERR2_HUMAN | ERRB2 | ESRL2 | ESRRB | Estrogen receptor-like 2 | Estrogen-related receptor beta | NR3B2 | Nuclear receptor subfamily 3 group B member 2 | Steroid hormone receptor ERR2 | Steroid hormone receptor ERR2 Beta
Type:
PROTEIN
Mol. Mass.:
48061.77
Organism:
Homo sapiens (Human)
Description:
ChEMBL_11254
Residue:
433
Sequence:
MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPPMFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVPMHKLFLEMLEAKV
  
Inhibitor
Name:
BDBM312137
Synonyms:
6-hydroxy-2-(4-hydroxyphenyl)-4-phenylisoquinolin-1(2H)-one | US9604931, 15a | US9623021, Compound 15b
Type:
Small organic molecule
Emp. Form.:
C21H15NO3
Mol. Mass.:
329.3487
SMILES:
Oc1ccc(cc1)-n1cc(-c2ccccc2)c2cc(O)ccc2c1=O
Structure:
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