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TargetProstaglandin E2 receptor EP2 subtype
LigandBDBM179991
Substrate/Competitorn/a
Meas. Tech.SEAP Activity Assay
EC50 2280±n/a nM
Citation Barrett, SDGermain, BDUzieblo, ACiske, FLEndres, GWKornilov, AMaxey, KMO'Malley, JPOwen, TA Lactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions US Patent US9676712 Publication Date 6/13/2017
More Info.:Get all data from this article,  Assay Method
 
Prostaglandin E2 receptor EP2 subtype
Name:Prostaglandin E2 receptor
Synonyms:PGE receptor EP2 subtype | PTGER2 | Prostaglandin E2 | Prostanoid EP2 Receptor
Type:Enzyme
Mol. Mass.:39775.71
Organism:Homo sapiens (Human)
Description:P43116
Residue:358
Sequence:
MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR
RSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFS
LATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQ
YCPGTWCFIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGS
GRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQA
LRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDASKQADL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM179991
NameBDBM179991
Synonyms:US9676712, 4C
TypeSmall organic molecule
Emp. Form.C26H33NO4S
Mol. Mass.455.61
SMILESCC(CCCc1ccccc1)[C@@H](O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(s1)C(O)=O |r|
Structure
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