Reaction Details Report a problem with these data
Target
Fatty acid-binding protein 5
Ligand
BDBM312340
Substrate
n/a
Meas. Tech.
Time Resolved-Fluorescence Energy Transfer (TR-FRET) Assay
IC50
20.0±n/a nM
Citation
 Buettelmann, B; Ceccarelli, SM; Kuehne, H; Kuhn, B; Neidhart, W; Obst Sander, U; Richter, H Bicyclic thiophenylamide compounds US Patent  US9604977 Publication Date 3/28/2017 
Target
Name:
Fatty acid-binding protein 5
Synonyms:
FABP5 | FABP5_HUMAN | Fatty acid binding protein epidermal | Fatty acid-binding protein 5 (FABP5)
Type:
Enzyme
Mol. Mass.:
15164.79
Organism:
Homo sapiens (Human)
Description:
Q01469
Residue:
135
Sequence:
MATVQQLEGRWRLVDSKGFDEYMKELGVGIALRKMGAMAKPDCIITCDGKNLTIKTESTLKTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLKDGKLVVECVMNNVTCTRIYEKVE
  
Inhibitor
Name:
BDBM312340
Synonyms:
2-[3-(4-Trifluoromethyl-thiazol-2-yl)-4,5,6,7-tetrahydro-benzo[b]thiophen-2-ylcarbamoyl]-cyclohex-1-enecarboxylic acid | US9604977, Example 86
Type:
Small organic molecule
Emp. Form.:
C20H19F3N2O3S2
Mol. Mass.:
456.502
SMILES:
OC(=O)C1=C(CCCC1)C(=O)Nc1sc2CCCCc2c1-c1nc(cs1)C(F)(F)F |t:3|
Structure:
Search PDB for entries with ligand similarity: