Reaction Details Report a problem with these data
Target
Bromodomain-containing protein 3 [51-123]
Ligand
BDBM313778
Substrate
n/a
Meas. Tech.
Binding Assay
IC50
<100±n/a nM
Citation
 Burns, C; Garnier, J; Sharp, PP; Feutrill, J; Cuzzupe, A Benzodiazepines as bromodomain inhibitors US Patent  US10167292 Publication Date 1/1/2019 
Target
Name:
Bromodomain-containing protein 3 [51-123]
Synonyms:
BRD3 | BRD3_HUMAN | Bromodomain-containing protein 3 (BRD3)(BD1) | Bromodomain-containing protein 3 Bromo 1 domain(BRD3 BD1) | KIAA0043 | RING3L
Type:
n/a
Mol. Mass.:
8887.10
Organism:
Homo sapiens (Human)
Description:
BD1 (51-123 aa) of Q15059
Residue:
73
Sequence:
WKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIV
  
Inhibitor
Name:
BDBM313778
Synonyms:
US10167292, Example 13
Type:
Small organic molecule
Emp. Form.:
C18H17ClN4
Mol. Mass.:
324.807
SMILES:
C[C@H]1CN(c2ccc(Cl)cc2)c2ccccc2-c2c(C)nnn12 |r|
Structure:
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