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Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM314366
Substrate
n/a
Meas. Tech.
Binding Assay
Ki
10.8±n/a nM
Citation
 Torrens-Jover, A; Christmann, U; Diaz-Fernández, J; Almansa-Rosales, C 1,2,3-triazole-4-amine derivatives for the treatment of sigma receptor related diseases and disorders US Patent  US9611229 Publication Date 4/4/2017 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Opioid receptor, sigma 1 | Oprs1 | SGMR1_MOUSE | Sigma 1-type opioid receptor | Sigma1-receptor | Sigma1R | Sigmar1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25246.51
Organism:
Mus musculus (Mouse)
Description:
O55242
Residue:
223
Sequence:
MPWAAGRRWAWITLILTIIAVLIQAAWLWLGTQNFVFSREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCILHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWKEGTTKSEVFYPGETVVHGPGEATALEWGPNTWMVEYGRGVIPSTLFFALADTFFSTQDYLTLFYTLRAYARGLRLELTTYLFGQDS
  
Inhibitor
Name:
BDBM314366
Synonyms:
N-(2-(azepan-1- yl)ethyl)-1-(1- adamantyl)-1H- 1,2,3-triazol-4-amine hydrochloride | US9611229, 14
Type:
Small organic molecule
Emp. Form.:
C20H33N5
Mol. Mass.:
343.5095
SMILES:
C(CN1CCCCCC1)Nc1cn(nn1)C12CC3CC(CC(C3)C1)C2 |TLB:22:21:16.17.18:24,THB:20:21:16:18.19.24|
Structure:
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