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Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM317228
Substrate
n/a
Meas. Tech.
Binding Assay
Ki
190±n/a nM
Citation
 Alcalde-Pais, M; Diaz Fernández, JL; Mesquida-Estevez, M; Paloma-Romeu, L Imidazo[2,1-b]thiazole derivatives, their preparation and use as medicaments US Patent  US9617281 Publication Date 4/11/2017 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:
Protein
Mol. Mass.:
25307.17
Organism:
Cavia porcellus (Guinea pig)
Description:
Q60492
Residue:
223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSKLIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
  
Inhibitor
Name:
BDBM317228
Synonyms:
2-Phenyl-6-((2- (pyrrolidin-1- yl)ethoxy)methyl) imidazo[2,1-b] thiazole maleate | US9617281, Compound 10
Type:
Small organic molecule
Emp. Form.:
C18H21N3OS
Mol. Mass.:
327.444
SMILES:
C(CN1CCCC1)OCc1cn2cc(sc2n1)-c1ccccc1
Structure:
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