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TargetAmine oxidase [flavin-containing] B
LigandBDBM11022
Substrate/CompetitorBDBM10999
Meas. Tech.MAO Inhibition Assay
pH7.5±n/a
Temperature298.15±n/a K
Ki 3000±n/a nM
Citation Hubalek, FBinda, CKhalil, ALi, MMattevi, ACastagnoli, NEdmondson, DE Demonstration of isoleucine 199 as a structural determinant for the selective inhibition of human monoamine oxidase B by specific reversible inhibitors. J Biol Chem280:15761-6 (2005) [PubMed]  Article
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Amine oxidase [flavin-containing] B
Name:Amine oxidase [flavin-containing] B
Synonyms:MAO-B | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:Protein
Mol. Mass.:58768.76
Organism:Homo sapiens (Human)
Description:P27338
Residue:520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
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BDBM11022
NameBDBM11022
Synonyms:2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | Isatin | Isatin (Compound 1)
TypeSmall organic molecule
Emp. Form.C8H5NO2
Mol. Mass.147.1308
SMILESO=C1Nc2ccccc2C1=O
Structure
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BDBM10999
NameBDBM10999
Synonyms:Benzenemethanamine | CHEMBL522 | benzylamine | phenylmethanamine
TypeSmall organic molecule
Emp. Form.C7H9N
Mol. Mass.107.1531
SMILESNCc1ccccc1
Structure
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