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Target5-hydroxytryptamine receptor 1A (5-HT1A)
LigandBDBM319745
Substrate/Competitorn/a
Meas. Tech.5-HT1A Receptor Agonism Activity Test
EC50 1.02±n/a nM
Citation Jiang, HWang, ZLi, JZhang, RHe, YLiu, YBi, MLiu, ZTian, GChen, WYang, FWu, CWang, YJiang, XYin, JWang, GShen, J Heterocyclic compounds, process for preparation of the same and use thereof US Patent US10174011 Publication Date 1/8/2019
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 1A (5-HT1A)
Name:5-hydroxytryptamine receptor 1A (5-HT1A)
Synonyms:5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A
Type:n/a
Mol. Mass.:46122.49
Organism:Homo sapiens (human)
Description:n/a
Residue:422
Sequence:
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
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BDBM319745
NameBDBM319745
Synonyms:1-(benzo[b]thiophen-4-yl)-4-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butyl)piperazinehydrochloride | US10174011, Example 138
TypeSmall organic molecule
Emp. Form.C23H32N6S
Mol. Mass.424.605
SMILESC(CCc1nnnn1C1CCCCC1)CN1CCN(CC1)c1cccc2sccc12
Structure
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n/a