Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM321283
Substrate
n/a
Meas. Tech.
Binding Assay to Sigma Receptors
Ki
360±n/a nM
Citation
 Melnyk, P; Vermersch, P; Carato, P; Oxombre-Vanteghem, B; Zephir, H; Donnier-Marechal, M Compounds, pharmaceutical composition and their use in treating neurodegenerative diseases US Patent  US10179761 Publication Date 1/15/2019 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20857.20
Organism:
Homo sapiens (Human)
Description:
Q5BJF2
Residue:
176
Sequence:
MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
  
Inhibitor
Name:
BDBM321283
Synonyms:
N-[3-(benzylmethylamino)propyl]-4-nitrobenzamide | US10179761, Compound 3.1.32
Type:
Small organic molecule
Emp. Form.:
C18H21N3O3
Mol. Mass.:
327.3776
SMILES:
CN(CCCNC(=O)c1ccc(cc1)[N+]([O-])=O)Cc1ccccc1
Structure:
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