Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM322984
Substrate
n/a
Meas. Tech.
cAMP Assay
EC50
317±n/a nM
Citation
 Grether, U; Nettekoven, M; Rogers-Evans, M; Schmitt, S; Stenton, BJ Triazolo[4,5-D]pyrimidines US Patent  US10183946 Publication Date 1/22/2019 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM322984
Synonyms:
2-[[5-tert-butyl-7-(2-methylpyrazol-3-yl)triazolo[4,5-d]pyrimidin-3-yl]methyl]-5-methyl-1,3,4-oxadiazole | US10183946, Example 15
Type:
Small organic molecule
Emp. Form.:
C16H19N9O
Mol. Mass.:
353.3818
SMILES:
Cc1nnc(Cn2nnc3c(nc(nc23)C(C)(C)C)-c2ccnn2C)o1
Structure:
Search PDB for entries with ligand similarity: