Reaction Details Report a problem with these data
Target
Melanocortin receptor 4
Ligand
BDBM323197
Substrate
n/a
Meas. Tech.
Transactivation Assay
EC50
4000±n/a nM
Citation
 Bouix-Peter, C; Suzuki, I; Rodeville, N; Mauvais, P; Pascal, J Oxoazetidine derivatives, process for the preparation thereof and use thereof in human medicine and in cosmetics US Patent  US9630949 Publication Date 4/25/2017 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM323197
Synonyms:
N-[(R)-1-(4-methoxybenzyl)-2-oxo-2-(3-pentyl-3-phenylazetidin-1-yl)ethyl]-3-(1H-imidazol-4-yl)propionamide | US9630949, 26
Type:
Small organic molecule
Emp. Form.:
C30H38N4O3
Mol. Mass.:
502.6477
SMILES:
CCCCCC1(CN(C1)C(=O)[C@@H](Cc1ccc(OC)cc1)NC(=O)CCc1c[nH]cn1)c1ccccc1
Structure:
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