Reaction Details Report a problem with these data
Target
Melanocyte-stimulating hormone receptor
Ligand
BDBM323255
Substrate
n/a
Meas. Tech.
Transactivation Assay
EC50
500±n/a nM
Citation
 Bouix-Peter, C; Suzuki, I; Rodeville, N; Mauvais, P; Pascal, J Oxoazetidine derivatives, process for the preparation thereof and use thereof in human medicine and in cosmetics US Patent  US9630949 Publication Date 4/25/2017 
Target
Name:
Melanocyte-stimulating hormone receptor
Synonyms:
MC1-R | MC1R | MSH-R | MSHR | MSHR_HUMAN | Melanocortin MC1 | Melanocortin receptor (M1 and M4) | Melanocortin receptor 1 (MC-1) | Melanocortin receptor 1 (MC1-R) | Melanocortin receptor 1 (MC1R)
Type:
Enzyme
Mol. Mass.:
34717.23
Organism:
Homo sapiens (Human)
Description:
Q01726
Residue:
317
Sequence:
MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTGARCLEVSISDGLFLSLGLVSLVENALVVATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAAVLQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVVFSTLFIAYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPVHQGFGLKGAVTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICNAIIDPLIYAFHSQELRRTLKEVLTCSW
  
Inhibitor
Name:
BDBM323255
Synonyms:
N-[1-(3-Butoxy-3-o-tolylazetidine-1-carbonyl)-2-hydroxy-2-(4-methoxyphenyl)ethyl]-3-(1H-imidazol-4-yl)propionamide | US9630949, 73
Type:
Small organic molecule
Emp. Form.:
C30H38N4O5
Mol. Mass.:
534.6465
SMILES:
CCCCOC1(CN(C1)C(=O)C(NC(=O)CCc1c[nH]cn1)C(O)c1ccc(OC)cc1)c1ccccc1C
Structure:
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