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TargetPPAR delta protein
LigandBDBM323594
Substrate/Competitorn/a
Meas. Tech.Luciferase Assay
EC50 45.1±n/a nM
Citation Downes, MEvans, RKluge, ALagu, BMiura, MPanigrahi, SKPatane, MSamajdar, SSenaiar, RTakahashi, T PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof US Patent US10188627 Publication Date 1/29/2019
More Info.:Get all data from this article,  Assay Method
 
PPAR delta protein
Name:PPAR delta protein
Synonyms:PPAR delta
Type:n/a
Mol. Mass.:49664.60
Organism:Rattus norvegicus (Rat)
Description:Q62879
Residue:440
Sequence:
MEQPQEETPEAREEEKEEVATGDGAPELNGGPEHTLPSSSCTDLSQNSSPSSLLDQLQMG
CDGASGGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLKYEKCDRICKIQKKN
RNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTASEGCQQNPQLADLKAFSKH
IYNAYLKNFNMTKKKARSILTGKSSHNAPFIIHDIETLWQAEKGLVWKQLVNGPPPYNEI
SVHVFYRCQSTTVETVRELTEFAKNIPNFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKD
GLLVANGSGFVTHEFLRSIRKPFSDIIEPKFEFAVKFNALELVDSDLALFIAAIILCGDR
PGLMNVPQVEAIQDTILQALEFHLQVNHPDSQYLFPKLLQKMADLRQLVTEHAQMMQWLK
KTESETLLHPLLQEIYKDMY
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM323594
NameBDBM323594
Synonyms:Synthesis of (E)-6-(2-((N,2-dimethylbenzofuran-5-carboxamido)methyl) phenoxy)-4-methylhex-4-enoic acid | US10188627, Compound 8f
TypeSmall organic molecule
Emp. Form.C25H27NO5
Mol. Mass.421.4856
SMILESCN(Cc1ccccc1OC\C=C(/C)CCC(O)=O)C(=O)c1ccc2oc(C)cc2c1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a