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TargetPPAR delta protein
LigandBDBM50192836
Substrate/Competitorn/a
Meas. Tech.Luciferase Assay
EC50 13.5±n/a nM
Citation Downes, MEvans, RKluge, ALagu, BMiura, MPanigrahi, SKPatane, MSamajdar, SSenaiar, RTakahashi, T PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof US Patent US10188627 Publication Date 1/29/2019  Article
More Info.:Get all data from this article,  Assay Method
 
PPAR delta protein
Name:PPAR delta protein
Synonyms:PPAR delta
Type:n/a
Mol. Mass.:49664.60
Organism:Rattus norvegicus (Rat)
Description:Q62879
Residue:440
Sequence:
MEQPQEETPEAREEEKEEVATGDGAPELNGGPEHTLPSSSCTDLSQNSSPSSLLDQLQMG
CDGASGGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLKYEKCDRICKIQKKN
RNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTASEGCQQNPQLADLKAFSKH
IYNAYLKNFNMTKKKARSILTGKSSHNAPFIIHDIETLWQAEKGLVWKQLVNGPPPYNEI
SVHVFYRCQSTTVETVRELTEFAKNIPNFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKD
GLLVANGSGFVTHEFLRSIRKPFSDIIEPKFEFAVKFNALELVDSDLALFIAAIILCGDR
PGLMNVPQVEAIQDTILQALEFHLQVNHPDSQYLFPKLLQKMADLRQLVTEHAQMMQWLK
KTESETLLHPLLQEIYKDMY
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50192836
NameBDBM50192836
Synonyms:CHEMBL3911672 | US10188627, Compound 8m
TypeSmall organic molecule
Emp. Form.C28H25NO5
Mol. Mass.455.5018
SMILESCN(Cc1ccccc1OCc1ccc(CC(O)=O)cc1)C(=O)c1ccc(cc1)-c1ccco1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a