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Target
Cystathionine gamma-lyase
Ligand
BDBM330336
Substrate
n/a
Meas. Tech.
In Vitro Assay
IC50
>100000±n/a nM
Citation
 Durón, SG; Chapman, J; Sydserff, SG; Rao, SG; Stein, G; Wade, W Cystathionine-γ-lyase (CSE) inhibitors US Patent  US9725426 Publication Date 8/8/2017 
Target
Name:
Cystathionine gamma-lyase
Synonyms:
CGL_HUMAN | CTH | Cystathionine gamma-lyase (CSE) | Cysteine-protein sulfhydrase | Gamma-cystathionase
Type:
Protein
Mol. Mass.:
44509.52
Organism:
Homo sapiens (Human)
Description:
P32929
Residue:
405
Sequence:
MQEKDASSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAAHPPSGSHS
  
Inhibitor
Name:
BDBM330336
Synonyms:
US9725426, (E)-5-(2-(benzo[d][1,3]dioxol-5-ylmethylene)hydrazinyl)-1H-tetrazole
Type:
Small organic molecule
Emp. Form.:
C9H8N6O2
Mol. Mass.:
232.1988
SMILES:
C1Oc2ccc(\C=N\Nc3nnn[nH]3)cc2O1
Structure:
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