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TargetG-protein coupled receptor 183
LigandBDBM332576
Substrate/Competitorn/a
Meas. Tech.Cell-Based Luminescent Assay
IC50 35±n/a nM
Citation Pinkerton, ABArdecky, RSergienko, EAGonzalez-Lopez, MGanji, SRZou, J Spirocyclic EBI2 modulators US Patent US10196369 Publication Date 2/5/2019
More Info.:Get all data from this article,  Assay Method
 
G-protein coupled receptor 183
Name:G-protein coupled receptor 183
Synonyms:EBI2
Type:PROTEIN
Mol. Mass.:41245.79
Organism:Homo sapiens (Human)
Description:ChEMBL_108311
Residue:361
Sequence:
MDIQMANNFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNR
KKINSTTLYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVN
FMTCLSIDRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERIT
CMEYPNFEETKSLPWILLGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNK
KALNTIILIIVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFN
CCMDPFIYFFACKGYKRKVMRMLKRQVSVSISSAVKSAPEENSREMTETQMMIHSKSSNG
K
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BDBM332576
NameBDBM332576
Synonyms:(2E)-3-(3,4-dichlorophenyl)-1-{7-[(4-(1H-1,2,3,4-tetraazol-5-yl)phenyl)carbonyl]-2,7-diazaspiro[3.5]non-2-yl}prop-2-en-1-one | US10196369, Compound C31
TypeSmall organic molecule
Emp. Form.C24H22Cl2N6O2
Mol. Mass.497.376
SMILESClc1ccc(\C=C\C(=O)N2CC3(C2)CCN(CC3)C(=O)c2ccc(cc2)-c2nnn[nH]2)cc1Cl
Structure
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n/a