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TargetG-protein coupled receptor 183
LigandBDBM332592
Substrate/Competitorn/a
Meas. Tech.Cell-Based Luminescent Assay
IC50 12.5±n/a nM
Citation Pinkerton, ABArdecky, RSergienko, EAGonzalez-Lopez, MGanji, SRZou, J Spirocyclic EBI2 modulators US Patent US10196369 Publication Date 2/5/2019
More Info.:Get all data from this article,  Assay Method
 
G-protein coupled receptor 183
Name:G-protein coupled receptor 183
Synonyms:EBI2
Type:PROTEIN
Mol. Mass.:41245.79
Organism:Homo sapiens (Human)
Description:ChEMBL_108311
Residue:361
Sequence:
MDIQMANNFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNR
KKINSTTLYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVN
FMTCLSIDRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERIT
CMEYPNFEETKSLPWILLGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNK
KALNTIILIIVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFN
CCMDPFIYFFACKGYKRKVMRMLKRQVSVSISSAVKSAPEENSREMTETQMMIHSKSSNG
K
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  Blast E-value cutoff:
BDBM332592
NameBDBM332592
Synonyms:5-bromoindol-2-yl 7-[(4-fluorophenyl)carbonyl]-2,7-diazaspiro[3.5]non-2-yl ketone | US10196369, Compound C47
TypeSmall organic molecule
Emp. Form.C23H21BrFN3O2
Mol. Mass.470.334
SMILESFc1ccc(cc1)C(=O)N1CCC2(CN(C2)C(=O)c2cc3cc(Br)ccc3[nH]2)CC1
Structure
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n/a