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TargetP2X purinoceptor 3
LigandBDBM271788
Substrate/Competitorn/a
Meas. Tech.Receptor Inhibition Assay
IC50 4.00±n/a nM
Citation Kai, H Aminotriazine derivative and pharmaceutical composition comprising the same US Patent US9732060 Publication Date 8/15/2017
More Info.:Get all data from this article,  Assay Method
 
P2X purinoceptor 3
Name:P2X purinoceptor 3
Synonyms:ATP receptor | P2RX3 | P2X purinoceptor 3 (P2RX3) | P2X purinoceptor 3 (P2X3) | P2X3 | P2X3 purinoceptor | Purinergic receptor
Type:Protein
Mol. Mass.:44292.02
Organism:Homo sapiens (Human)
Description:P56373
Residue:397
Sequence:
MNCISDFFTYETTKSVVVKSWTIGIINRVVQLLIISYFVGWVFLHEKAYQVRDTAIESSV
VTKVKGSGLYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPESEEKYRCVSDS
QCGPERLPGGGILTGRCVNYSSVLRTCEIQGWCPTEVDTVETPIMMEAENFTIFIKNSIR
FPLFNFEKGNLLPNLTARDMKTCRFHPDKDPFCPILRVGDVVKFAGQDFAKLARTGGVLG
IKIGWVCDLDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKA
FGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADQYKAKKFEE
VNETTLKIAALTNPVYPSDQTTAEKQSTDSGAFSIGH
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  Blast E-value cutoff:
BDBM271788
NameBDBM271788
Synonyms:US10065941, Compound R-099 | US9732060, Compound R-099
TypeSmall organic molecule
Emp. Form.C27H23ClN6O5
Mol. Mass.546.962
SMILESCOC(=O)[C@@H](C)Cn1c(=O)[nH]\c(=N/c2ccc(Oc3ccnc(c3)C#N)cc2)n(Cc2ccc(Cl)cc2)c1=O |r|
Structure
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