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Target
Nuclear receptor subfamily 2 group C member 1
Ligand
BDBM333428
Substrate
n/a
Meas. Tech.
Inhibition Assay
IC50
7000±n/a nM
Citation
 Traynelis, SF; Mullasseril, P; Garnier, EC; Liotta, DC; Zimmerman, S NMDA receptor modulators and uses related thereto US Patent  US9737522 Publication Date 8/22/2017 
Target
Name:
Nuclear receptor subfamily 2 group C member 1
Synonyms:
NR2C1_RAT | Nr2c1 | Nuclear receptor subfamily 2 group C member 1 (NR2C) | Tr2
Type:
Protein
Mol. Mass.:
65528.28
Organism:
Rattus norvegicus (Rat)
Description:
Q8VIJ4
Residue:
590
Sequence:
MATIEEIAHQIIDQQMGEIVTEQQTGQKIQIVTALDHSTQGKQFILANHEGSTPGKVFLTTPDAAGVNQLFFASPDLSTPHLQLLTENSPDQGPNKVFDLCVVCGDKASGRHYGAITCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQRCIAFGMKQDSVQCERKPIEVSREKSSNCAASTEKIYIRKDLRSPLAATPTFVTDSETARSTGLLDSGMFVNIHPSGIKTEPALLMTPDKAESCQGDLGTLASVVTSLANLGKAKDLSHCGGDLPVVQSLRNGDTSFGAFHQDIQTNGDVSRAFDNLAKALTPGENPACQSPGESMEGSTHLIAGEPSCMEREGPLLSDSHVVFRLTMPSPMPEYLNVHYIGESASRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNVATILATFVNCLHNSLQQDKMSPERRKLLMEHIFKLQEFCNSMVKLCIDGHEYAYLKAIVLFSPDHPGLENMELIEKFQEKAYVEFQDYITRTYPDDTYRLSRLLLRLPALRLMNATITEELFFKGLIGNVRIDSVIPHILKMEPADYNSQIIGHSL
  
Inhibitor
Name:
BDBM333428
Synonyms:
US9737522, Compound 2
Type:
Small organic molecule
Emp. Form.:
C29H27N3O3
Mol. Mass.:
465.543
SMILES:
CCc1ccc(cc1)C1N(CCc2c[nH]c3cc(C)ccc23)C(=O)C(O)=C1C(=O)c1cccnc1 |c:28|
Structure:
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