Reaction Details Report a problem with these data
Target
Amyloid beta-binding alcohol dehydrogenase
Ligand
BDBM232924
Substrate
n/a
Meas. Tech.
Assay of ABAD Enzymatic Activity
IC50
335000±n/a nM
Citation
 Yan, S; Valasani, KR Phosphonate derivatives and methods of use thereof in the treatment of Alzheimer's disease US Patent  US9738668 Publication Date 8/22/2017 
Target
Name:
Amyloid beta-binding alcohol dehydrogenase
Synonyms:
Amyloid beta-binding alcohol dehydrogenase (ABAD)
Type:
Enzyme
Mol. Mass.:
938.17
Organism:
Homo sapiens (Human)
Description:
Q2L8D9
Residue:
9
Sequence:
MAAACRSVK
  
Inhibitor
Name:
BDBM232924
Synonyms:
US9346839, 5 | US9738668, Compound 5
Type:
Small organic molecule
Emp. Form.:
C18H18FN2O6PS
Mol. Mass.:
440.382
SMILES:
COC(=O)c1cc(ccc1O)[C@H](Nc1nc2cc(F)ccc2s1)P(=O)(OC)OC |r|
Structure:
Search PDB for entries with ligand similarity: