Reaction Details Report a problem with these data
Target
Kallikrein-7
Ligand
BDBM336221
Substrate
n/a
Meas. Tech.
Inhibition Assay
IC50
11200±n/a nM
Citation
 Linschoten, M Kallikrein 7 inhibitors US Patent  US9744148 Publication Date 8/29/2017 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM336221
Synonyms:
US9744148, 90
Type:
Small organic molecule
Emp. Form.:
C22H19NO3
Mol. Mass.:
345.3912
SMILES:
O=C(COC(=O)C(c1ccccc1)c1ccccc1)Nc1ccccc1
Structure:
Search PDB for entries with ligand similarity: