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TargetRetinaldehyde-binding protein 1
LigandBDBM339025
Substrate/Competitorn/a
Meas. Tech.Isomerase Assay
IC50<500000±n/a nM
Citation Scott, ILKuksa, VAGall, AOrme, MWGage, JLittle, Jr., TLJiang, QRossiter, LMMcGee, Jr., KFKubota, R Styrenyl derivative compounds for treating ophthalmic diseases and disorders US Patent US10201545 Publication Date 2/12/2019
More Info.:Get all data from this article,  Assay Method
 
Retinaldehyde-binding protein 1
Name:Retinaldehyde-binding protein 1
Synonyms:CRALBP | Cellular retinaldehyde-binding protein | RLBP1
Type:Enzyme Catalytic Domain
Mol. Mass.:36462.25
Organism:Homo sapiens (Human)
Description:P12271
Residue:317
Sequence:
MSEGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREETRE
EAVRELQEMVQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNF
RLQYPELFDSLSPEAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQSQEITFDEILQAY
CFILEKLLENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSFPARFKAIHF
IHQPWYFTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENILPSDFGGTLPKYDGKA
VAEQLFGPQAQAENTAF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM339025
NameBDBM339025
Synonyms:(E)-4-amino-1,1,1-trifluoro-2-(3-(2-(2,6,6- trimethylcyclohex-1-enyl)vinyl)phenyl)butan-2-ol | US10201545, Compound 57
TypeSmall organic molecule
Emp. Form.C21H28F3NO
Mol. Mass.367.4483
SMILESCC1=C(\C=C\c2cccc(c2)C(O)(CCN)C(F)(F)F)C(C)(C)CCC1 |c:1|
Structure
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