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TargetACT1
LigandBDBM65515
Substrate/Competitorn/a
Meas. Tech.Liquid growth assay
Temperature303.15±0 K
IC50 70±0.0 nM
Citation Filipuzzi, IThomas, JRPries, VEstoppey, DSalcius, MStuder, CSchirle, MHoepfner, D Direct Interaction of Chivosazole F with Actin Elicits Cell Responses Similar to Latrunculin A but Distinct from Chondramide. ACS Chem Biol12:2264-2269 (2017) [PubMed]  Article
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
ACT1
Name:ACT1
Synonyms:Actin
Type:Protein
Mol. Mass.:41683.13
Organism:Baker's yeast
Description:P60010
Residue:375
Sequence:
MDSEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGIMVGMGQKDSYVGDEAQS
KRGILTLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPMNPKSNREKMT
QIMFETFNVPAFYVSIQAVLSLYSSGRTTGIVLDSGDGVTHVVPIYAGFSLPHAILRIDL
AGRDLTDYLMKILSERGYSFSTTAEREIVRDIKEKLCYVALDFEQEMQTAAQSSSIEKSY
ELPDGQVITIGNERFRAPEALFHPSVLGLESAGIDQTTYNSIMKCDVDVRKELYGNIVMS
GGTTMFPGIAERMQKEITALAPSSMKVKIIAPPERKYSVWIGGSILASLTTFQQMWISKQ
EYDESGPSIVHHKCF
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  Blast E-value cutoff:
BDBM65515
NameBDBM65515
Synonyms:76343-93-6 | LAT-A | LatA | Latrunculin A
TypeSmall organic molecule
Emp. Form.C22H31NO5S
Mol. Mass.421.55
SMILESC[C@H]1CC[C@@H]2C[C@H](C[C@@](O)(O2)[C@@H]2CSC(=O)N2)OC(=O)\C=C(C)/CC\C=C\C=C/1 |c:29,t:22,27|
Structure
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n/a