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TargetLarge neutral amino acids transporter small subunit 1
LigandBDBM340533
Substrate/Competitorn/a
Meas. Tech.Inhibitory Activity Assay
IC50 89100±n/a nM
Citation Kanai, YNagamori, SKitaura, YNeya, MMatsushita, N Phenoxyalkylamine compound US Patent US9771316 Publication Date 9/26/2017  Article
More Info.:Get all data from this article,  Assay Method
 
Large neutral amino acids transporter small subunit 1
Name:Large neutral amino acids transporter small subunit 1
Synonyms:4F2 LC | 4F2 light chain | 4F2LC | CD98 light chain | CD98LC | Integral membrane protein E16 | L-type amino acid transporter 1 | LAT1 | Large neutral amino acids transporter small subunit 1 | MPE16 | SLC7A5 | Solute carrier family 7 member 5 | hLAT1 | y+ system cationic amino acid transporter
Type:PROTEIN
Mol. Mass.:55013.61
Organism:Homo sapiens (Human)
Description:ChEMBL_100160
Residue:507
Sequence:
MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIV
GTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYM
LEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVL
LLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDV
GNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTL
STEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLP
SILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRH
RKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKN
KPKWLLQGIFSTTVLCQKLMQVVPQET
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BDBM340533
NameBDBM340533
Synonyms:US9771316, Example 6
TypeSmall organic molecule
Emp. Form.C19H22F3NO
Mol. Mass.337.3793
SMILESNCCCCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1
Structure
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