Reaction Details Report a problem with these data
Target
D-amino-acid oxidase
Ligand
BDBM50431079
Substrate
n/a
Meas. Tech.
DAAO Inhibitory Activity Assay
IC50
3.90±n/a nM
Citation
 Hondo, T; Nakanishi, K; Niimi, T; Warizaya, M; Namatame, I; Harada, K Dihydroxy aromatic heterocyclic compound US Patent  US10202399 Publication Date 2/12/2019 
Target
Name:
D-amino-acid oxidase
Synonyms:
D-amino-acid oxidase (DAAO) | DAAO | DAMOX | DAO | OXDA_HUMAN
Type:
Homodimer
Mol. Mass.:
39476.06
Organism:
Homo sapiens (Human)
Description:
P14920
Residue:
347
Sequence:
MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPNNPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPRELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVNCTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGGIFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGPSNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL
  
Inhibitor
Name:
BDBM50431079
Synonyms:
CHEMBL2338785 | US10202399, Example 9 | US9180122, 27 | US9212147, 9
Type:
Small organic molecule
Emp. Form.:
C13H13NO2
Mol. Mass.:
215.2478
SMILES:
Oc1cc(CCc2ccccc2)c[nH]c1=O
Structure:
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