Reaction Details Report a problem with these data
Target
Protein M2-1
Ligand
BDBM347287
Substrate
n/a
Meas. Tech.
Cytopathic Effect Assay with RSV A2 in HEp-2 Cells
EC50
>100000±n/a nM
Citation
 Sommadossi, J; Moussa, A β-D-2′-deoxy-2′-substituted-4′-substituted-2-substituted-N6-substituted-6-aminopurinenucleotides for the treatment of paramyxovirus and orthomyxovirus infections US Patent  US10202412 Publication Date 2/12/2019 
Target
Name:
Protein M2-1
Synonyms:
Envelope-associated 22 kDa protein | M2-1 | M21_HRSVA | Matrix M2-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22163.59
Organism:
Human respiratory syncytial virus A (strain A2)
Description:
P04545
Residue:
194
Sequence:
MSRRNPCKFEIRGHCLNGKRCHFSHNYFEWPPHALLVRQNFMLNRILKSMDKSIDTLSEISGAAELDRTEEYALGVVGVLESYIGSINNITKQSACVAMSKLLTELNSDDIKKLRDNEELNSPKIRVYNTVISYIESNRKNNKQTIHLLKRLPADVLKKTIKNTLDIHKSITINNPKESTVSDTNDHAKNNDTT
  
Inhibitor
Name:
BDBM347287
Synonyms:
US10202412, Compound C
Type:
Small organic molecule
Emp. Form.:
C12H17FN6O3
Mol. Mass.:
312.3002
SMILES:
CNc1nc(N)nc2n(cnc12)[C@@H]1O[C@](C)(CO)[C@@H](O)[C@H]1F |r|
Structure:
Search PDB for entries with ligand similarity: