Reaction Details Report a problem with these data
Target
Somatostatin receptor type 1
Ligand
BDBM312012
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
6670±n/a nM
Citation
 Giovannini, R; Cui, Y; Doods, H; Ferrara, M; Just, S; Kuelzer, R; Lingard, I; Mazzaferro, R; Rudolf, K Somatostatin receptor subtype 4 (SSTR4) agonists US Patent  US9789082 Publication Date 10/17/2017 
Target
Name:
Somatostatin receptor type 1
Synonyms:
SOMATOSTATIN SST1 | SRIF-2 | SS-1-R | SS1-R | SS1R | SSR1_HUMAN | SSTR1 | Somatostatin receptor type 1 (SSTR1)
Type:
Enzyme
Mol. Mass.:
42692.81
Organism:
Homo sapiens (Human)
Description:
P30872
Residue:
391
Sequence:
MFPNGTASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGVFRNGTCTSRITTL
  
Inhibitor
Name:
BDBM312012
Synonyms:
US10166214, Example 148 | US10675268, Example 148 | US9789082, Example 148
Type:
Small organic molecule
Emp. Form.:
C19H24N4O
Mol. Mass.:
324.4201
SMILES:
Cc1nc(c2cccc(C)c2n1)C(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12 |r|
Structure:
Search PDB for entries with ligand similarity: