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Target
Prokineticin receptor 1
Ligand
BDBM347576
Substrate
n/a
Meas. Tech.
Biological Assay
IC50
100.0±n/a nM
Citation
 Bousba, S; Goldby, A; Jenkins, K; Kinsella, N; Teall, M Piperidine and azepine derivatives as prokineticin receptor modulators US Patent  US9790201 Publication Date 10/17/2017 
Target
Name:
Prokineticin receptor 1
Synonyms:
G-protein coupled receptor 73 | G-protein coupled receptor ZAQ | GPR73 | GPR73a | PK-R1 | PKR1 | PKR1_HUMAN | PROKR1
Type:
enzyme
Mol. Mass.:
44779.92
Organism:
Homo sapiens (Human)
Description:
Q8TCW9
Residue:
393
Sequence:
METTMGFMDDNATNTSTSFLSVLNPHGAHATSFPFNFSYSDYDMPLDEDEDVTNSRTFFAAKIVIGMALVGIMLVCGIGNFIFIAALVRYKKLRNLTNLLIANLAISDFLVAIVCCPFEMDYYVVRQLSWEHGHVLCTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTATGLIALVWTVSILIAIPSAYFTTETVLVIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGIEFVGPVVTMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDFFPTVFVKEKHYLTAFYIVECIAMSNSMINTLCFVTVKNDTVKYFKKIMLLHWKASYNGGKSSADLDLKTIGMPATEEVDCIRLK
  
Inhibitor
Name:
BDBM347576
Synonyms:
4-({3-[4-Methoxy-2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)-N,N-dimethylpyridin-2-amine | US9790201, 62
Type:
Small organic molecule
Emp. Form.:
C21H24F3N3O2
Mol. Mass.:
407.4294
SMILES:
COc1ccc(C2CCCN(C2)C(=O)c2ccnc(c2)N(C)C)c(c1)C(F)(F)F
Structure:
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