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Target
Trace amine-associated receptor 1
Ligand
BDBM348691
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
IC50
5.20±n/a nM
Citation
 Cecere, G; Galley, G; Hu, Y; Norcross, R; Pflieger, P; Shen, H 2-oxa-5-azabicyclo[2.2.1]heptan-3-yl derivatives US Patent  US9790230 Publication Date 10/17/2017 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TAAR1_RAT | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1
Type:
Enzyme
Mol. Mass.:
38034.73
Organism:
Rattus norvegicus (Rat)
Description:
Q923Y9
Residue:
332
Sequence:
MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWLLHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDRYYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRGCFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQSKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMVYAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM348691
Synonyms:
(1S,3R,4S)-3-(4-Bromophenyl)-2-oxa-5-azabicyclo[2.2.1]heptane | US9790230, Example 53
Type:
Small organic molecule
Emp. Form.:
C11H12BrNO
Mol. Mass.:
254.123
SMILES:
Brc1ccc(cc1)[C@H]1O[C@@H]2CN[C@H]1C2 |r|
Structure:
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