Reaction Details Report a problem with these data
Target
G-protein coupled estrogen receptor 1
Ligand
BDBM349630
Substrate
n/a
Meas. Tech.
Human ERalpha Reporter Assa
IC50
<1000±n/a nM
Citation
 Strum, JC Benzothiophene estrogen receptor modulators US Patent  US10208011 Publication Date 2/19/2019 
Target
Name:
G-protein coupled estrogen receptor 1
Synonyms:
CEPR | CMKRL2 | DRY12 | G-protein coupled estrogen receptor 1 | G-protein-coupled receptor (GPR30 ) | GPER | GPER1 | GPER1_HUMAN | GPR30
Type:
PROTEIN
Mol. Mass.:
42259.21
Organism:
Homo sapiens (Human)
Description:
ChEMBL_982507
Residue:
375
Sequence:
MDVTSQARGVGLEMYPGTAQPAAPNTTSPELNLSHPLLGTALANGTGELSEHQQYVIGLFLSCLYTIFLFPIGFVGNILILVVNISFREKMTIPDLYFINLAVADLILVADSLIEVFNLHERYYDIAVLCTFMSLFLQVNMYSSVFFLTWMSFDRYIALARAMRCSLFRTKHHARLSCGLIWMASVSATLVPFTAVHLQHTDEACFCFADVREVQWLEVTLGFIVPFAIIGLCYSLIVRVLVRAHRHRGLRPRRQKALRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRHAHPLTGHIVNLAAFSNSCLNPLIYSFLGETFRDKLRLYIEQKTNLPALNRFCHAALKAVIPDSTEQSDVRFSSAV
  
Inhibitor
Name:
BDBM349630
Synonyms:
US10208011, Compound RAD- | US10981887, Compound RAD-
Type:
Small organic molecule
Emp. Form.:
C30H38N2O2
Mol. Mass.:
458.6349
SMILES:
CCNCCc1ccc(CN(CC)c2cc(OC)ccc2[C@@H]2CCc3cc(O)ccc3C2)cc1 |r|
Structure:
Search PDB for entries with ligand similarity: