Target
N-formyl peptide receptor 2
Ligand
BDBM350548
Substrate
n/a
Meas. Tech.
FLIPR
EC50
11000±n/a nM
Citation
 Beard, RLDonello, JEViswanath, V Use of agonists of formyl peptide receptor 2 for treating ocular inflammatory diseases US Patent  US10208071 Publication Date 2/19/2019 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM350548
Synonyms:
2-{[(4- bromophenyl)carbamoyl]amino}-N- (2-oxoazepan-3-yl)-3- phenylpropanamide | US10208071, Compound 10 | US10434112, Compound 10 | US10799518, Compound 10
Type:
Small organic molecule
Emp. Form.:
C22H25BrN4O3
Mol. Mass.:
473.363
SMILES:
Brc1ccc(NC(=O)NC(Cc2ccccc2)C(=O)NC2CCCCNC2=O)cc1
Structure:
Search PDB for entries with ligand similarity: