Target
N-formyl peptide receptor 2
Ligand
BDBM350564
Substrate
n/a
Meas. Tech.
FLIPR
EC50
4800±n/a nM
Citation
 Beard, RLDonello, JEViswanath, V Use of agonists of formyl peptide receptor 2 for treating ocular inflammatory diseases US Patent  US10208071 Publication Date 2/19/2019 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM350564
Synonyms:
N-(4-bromophenyl) spiro[bicyclo[2.2.1]heptane- 7,1'-cyclopropane]-5-ene-2,3- dicarboxamide | US10208071, Compound 26 | US10434112, Compound 26
Type:
Small organic molecule
Emp. Form.:
C17H17BrN2O2
Mol. Mass.:
361.233
SMILES:
NC(=O)C1C2C=CC(C1C(=O)Nc1ccc(Br)cc1)C21CC1 |c:5,TLB:9:8:6.5:19,THB:1:3:6.5:19|
Structure:
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