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Target
N-formyl peptide receptor 2
Ligand
BDBM350575
Substrate
n/a
Meas. Tech.
FLIPR
EC50
17000±n/a nM
Citation
 Beard, RL; Donello, JE; Viswanath, V Use of agonists of formyl peptide receptor 2 for treating ocular inflammatory diseases US Patent  US10208071 Publication Date 2/19/2019 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM350575
Synonyms:
7,7-dimethyl-N-[4-(methylsulfanyl) phenyl]bicyclo[2.2.1]heptane- 2,3-dicarboxamide | US10208071, Compound 37 | US10434112, Compound 37 | US10799518, Compound 37
Type:
Small organic molecule
Emp. Form.:
C18H24N2O2S
Mol. Mass.:
332.46
SMILES:
CSc1ccc(NC(=O)C2C3CCC(C2C(N)=O)C3(C)C)cc1 |TLB:7:9:11.12:18,THB:15:14:11.12:18|
Structure:
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