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Target
5-hydroxytryptamine receptor 7
Ligand
BDBM352201
Substrate
n/a
Meas. Tech.
Radiolabel Binding Assay
IC50
565±n/a nM
Citation
 Canney, DJ; Blass, BE; Gao, R; Abou-Gharbia, M 5-hydroxytryptamine receptor 7 activity modulators and their method of use US Patent  US9802924 Publication Date 10/31/2017 
Target
Name:
5-hydroxytryptamine receptor 7
Synonyms:
5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
53573.08
Organism:
Homo sapiens (Human)
Description:
P34969
Residue:
479
Sequence:
MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
  
Inhibitor
Name:
BDBM352201
Synonyms:
US10239868, Entry 5 | US10287274, Entry 5 | US10676464, Entry 5 | US9802924, Entry 5
Type:
Small organic molecule
Emp. Form.:
C22H34N2O2
Mol. Mass.:
358.5176
SMILES:
CCC1(CC)CC(CCN2CCN(CCc3ccccc3)CC2)OC1=O
Structure:
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