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Target
Androgen receptor
Ligand
BDBM354701
Substrate
n/a
Meas. Tech.
Binding Assay
IC50
367±n/a nM
Citation
 Choi, SP; Choi, SM; Son, BH; Kim, HJ; Kim, JM; Jang, BJ; Sung, JH; Lee, JH; Kim, E; Kang, KK; Kim, S Oxazolidine-based compound and selective androgen receptor agonist comprising same US Patent  US9809583 Publication Date 11/7/2017 
Target
Name:
Androgen receptor
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
97086.15
Organism:
Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus)
Description:
A0A0D9RHK8
Residue:
900
Sequence:
MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLQQQQQQQQQQQQQQETSPRQQQKQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSAPECHPERGCVPEPGAAVAAGKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQLLQQQQQEAVSEGSSNGRAREASGAPTSSKDNYLGGTSTISDSAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPVLGVPPGVRPIPCAPLAECKGSLLDDSAGKSTEDTVEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGAGEAGAVAPYGYTRPPQGLAGQEGDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETAQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ
  
Inhibitor
Name:
BDBM354701
Synonyms:
Preparation of 4-(((2R,5S)-3-(4-cyano-3-(trifluoromethyl)phenyl)-2-(trifluoromethyl)oxazolidin-5-yl)methoxy)benzoic acid | US9809583, Example 9
Type:
Small organic molecule
Emp. Form.:
C19H14F6N2O6
Mol. Mass.:
480.3147
SMILES:
OC(=O)c1ccc(OC[C@@H]2CN([C@H](O2)C(F)(F)F)c2ccc(c(c2)C(F)(F)F)[N+]([O-])=O)cc1 |r|
Structure:
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