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TargettRNA synthetase (GlyRS)
LigandBDBM18135
Substrate/CompetitorBDBM18133
Meas. Tech.In Vitro Enzyme Activity Assay
pH7.5±n/a
Temperature298.15±n/a K
Ki 800±n/a nM
IC50 10000±n/a nM
Citation Dignam, JDNada, SChaires, JB Thermodynamic characterization of the binding of nucleotides to glycyl-tRNA synthetase. Biochemistry42:5333-40 (2003) [PubMed]  Article
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
tRNA synthetase (GlyRS)
Name:tRNA synthetase (GlyRS)
Synonyms:Glycine--tRNA ligase | Glycyl-tRNA synthetase
Type:Enzyme
Mol. Mass.:76917.70
Organism:Bombyx mori
Description:B. mori glycyltRNA synthetase was expressed in E. coli.
Residue:680
Sequence:
MADPKIEEILAPLRANVKEQGDLVRKLKEEKAPEIDIKKAVAELKTRKKILEDKELSLAP
AEDLFDRAKMEDLIKRRFFYDQSFAIYGGITGQFDFGPMGCALKSNMIHLWKKFFILQEQ
MLEVECSILTPEPVLKASGHVERFADLMTKDIKTGECFRLDHLIKGHLEKIKSDKNTKIE
LKAEIEDILIKLDGMNADEMSALMKRFEMKSPISGNDLTPPIEFNLMFNTQIGPSGLVKG
FLRPETAQGIFVNFKRLLEFNQGRLPFAAAQIGNSFRNEISPRSGLLRVREFTMCEIEHF
CDVKEHPKFESVKNTQSLLYSADNQEQGKPADLTTIGDAVCKGIVNNETLGYFMARIHMY
MLAVGIDPKRLRFRQHMGNEMAHYACDCWDAECLSSYGWIECVGCADRSAYDLTQHTKAT
GIRLAAEKKLPAPKQIEVVEAIANNGRIGKAFKKDSQAINDTLATLDNAALEEMQKELDS
NGEYTLITARGEFKLTPSLVNVKKTQKTIHVEEIIPSVIEPSFGVGRILYCILEHNFRMR
EGDEQRTYFSLPPTVAPMKCVVLPLSGNAEFQPFVRDLSQELITVDVSHKVDDSSGSIGR
RYARTDELGVPYAVTVDFDTIKEPHTVTLRERDSMRQVRLPMADVPTVVRDLSNSKILWS
DVEQKYPKFEQQETVKGTSV
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BDBM18135
NameBDBM18135
Synonyms:({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}methyl)phosphonic acid | AMPPCP | ATP,Beta Gamma-me | CHEMBL133463 | adenylylmethylenediphosphonate
TypeNucleoside or nucleotide
Emp. Form.C11H18N5O12P3
Mol. Mass.505.2082
SMILESNc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)CP(O)(O)=O)[C@@H](O)[C@H]1O |r|
Structure
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BDBM18133
NameBDBM18133
Synonyms:2-aminoacetic acid | CHEMBL773 | Glycine | [14C]Glycine
TypeAmino Acid
Emp. Form.C2H5NO2
Mol. Mass.75.0666
SMILESNCC(O)=O
Structure
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