Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM362725
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
3.20±n/a nM
Citation
 Galley, G; Pflieger, P; Norcross, R; Cecere, G; Shen, H; Hu, Y Morpholin-pyridine derivatives US Patent  US9840501 Publication Date 12/12/2017 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TAAR1_RAT | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1
Type:
Enzyme
Mol. Mass.:
38034.73
Organism:
Rattus norvegicus (Rat)
Description:
Q923Y9
Residue:
332
Sequence:
MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWLLHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDRYYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRGCFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQSKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMVYAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM362725
Synonyms:
6-[(2S)-Morpholin-2-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-3-amine | US9840501, Example 19
Type:
Small organic molecule
Emp. Form.:
C16H16F3N3O
Mol. Mass.:
323.3129
SMILES:
FC(F)(F)c1ccc(Nc2ccc(nc2)[C@@H]2CNCCO2)cc1 |r|
Structure:
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