Target
Trace amine-associated receptor 1
Ligand
BDBM362747
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
5.00±n/a nM
Citation
 Galley, GPflieger, PNorcross, RCecere, GShen, HHu, Y Morpholin-pyridine derivatives US Patent  US9840501 Publication Date 12/12/2017 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TAAR1_RAT | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1
Type:
Enzyme
Mol. Mass.:
38034.73
Organism:
Rattus norvegicus (Rat)
Description:
Q923Y9
Residue:
332
Sequence:
MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWLLHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDRYYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRGCFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQSKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMVYAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM362747
Synonyms:
1-(3-Chlorophenyl)-3-[6-[(2S)-morpholin-2-yl]-3-pyridyl]urea | US9840501, Example 41
Type:
Small organic molecule
Emp. Form.:
C16H17ClN4O2
Mol. Mass.:
332.785
SMILES:
Clc1cccc(NC(=O)Nc2ccc(nc2)[C@@H]2CNCCO2)c1 |r|
Structure:
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