Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM362803
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
4.30±n/a nM
Citation
 Galley, G; Pflieger, P; Norcross, R; Cecere, G; Shen, H; Hu, Y Morpholin-pyridine derivatives US Patent  US9840501 Publication Date 12/12/2017 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TAAR1_MOUSE | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1
Type:
Protein
Mol. Mass.:
37635.41
Organism:
Mus musculus (Mouse)
Description:
Q923Y8
Residue:
332
Sequence:
MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM362803
Synonyms:
3-Butyl-N-[6-[(2R)-morpholin-2-yl]-3-pyridyl]-1H-pyrazole-5-carboxamide | US9840501, Example 97
Type:
Small organic molecule
Emp. Form.:
C17H23N5O2
Mol. Mass.:
329.3968
SMILES:
CCCCc1cc([nH]n1)C(=O)Nc1ccc(nc1)[C@H]1CNCCO1 |r|
Structure:
Search PDB for entries with ligand similarity: