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TargetLarge envelope protein
LigandBDBM246848
Substrate/Competitorn/a
Meas. Tech.HBsAg assay
Temperature298.15±n/a K
IC50 20.0±n/a nM
Commentsextracted
Citation Han, XJiang, MWang, YYang, S Tetracyclic 4-oxo-pyridine-3-carboxylic acid derivatives for the treatment and prophylaxis of hepatitis B virus infection US Patent US10053461 Publication Date 8/21/2018
More Info.:Get all data from this article,  Assay Method
 
Large envelope protein
Name:Large envelope protein
Synonyms:n/a
Type:n/a
Mol. Mass.:42772.52
Organism:Hepatitis B virus
Description:P03138
Residue:389
Sequence:
MGQNLSTSNPLGFFPDHQLDPAFRANTANPDWDFNPNKDTWPDANKVGAGAFGLGFTPPH
GGLLGWSPQAQGILQTLPANPPPASTNRQSGRQPTPLSPPLRNTHPQAMQWNSTTFHQTL
QDPRVRGLYFPAGGSSSGTVNPVLTTASPLSSIFSRIGDPALNMENITSGFLGPLLVLQA
GFFLLTRILTIPQSLDSWWTSLNFLGGTTVCLGQNSQSPTSNHSPTSCPPTCPGYRWMCL
RRFIIFLFILLLCLIFLLVLLDYQGMLPVCPLIPGSSTTSTGPCRTCMTTAQGTSMYPSC
CCTKPSDGNCTCIPIPSSWAFGKFLWEWASARFSWLSLLVPFVQWFVGLSPTVWLSVIWM
MWYWGPSLYSILSPFLPLLPIFFCLWVYI
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM246848
NameBDBM246848
Synonyms:Cis-10-methoxy-3,3,11-trimethyl-7-oxo-1,2,3,3a,7,12b-hexahydrocyclopenta[c]pyrido[2,1-a]isoquinoline-6-carboxylic acid | US10053461, 39
TypeSmall organic molecule
Emp. Form.C22H25NO4
Mol. Mass.367.4382
SMILESCCc1cc2[C@H]3CCC(C)(C)[C@H]3n3cc(C(O)=O)c(=O)cc3-c2cc1OC |r|
Structure
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n/a