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TargetHemagglutinin
LigandBDBM31148
Substrate/Competitorn/a
Meas. Tech.Endonuclease Assay
pH7.5±n/a
IC50 24000±n/a nM
Commentsextracted
Citation Lavoie, EJBauman, JDSagong, HYArnold, EParhi, ADas, KVijayan, SKPatel, D Therapeutic hydroxyquinolones US Patent US9701638 Publication Date 7/11/2017
More Info.:Get all data from this article,  Assay Method
 
Hemagglutinin
Name:Hemagglutinin
Synonyms:HA | Hemagglutinin HA1 chain
Type:Enzyme Catalytic Domain
Mol. Mass.:63281.44
Organism:Influenza A virus (strain swl A/California/04/2009 H1N1)
Description:C3W5S1
Residue:566
Sequence:
MKAILVVLLYTFATANADTLCIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDKHNGKLCK
LRGVAPLHLGKCNIAGWILGNPECESLSTASSWSYIVETPSSDNGTCYPGDFIDYEELRE
QLSSVSSFERFEIFPKTSSWPNHDSNKGVTAACPHAGAKSFYKNLIWLVKKGNSYPKLSK
SYINDKGKEVLVLWGIHHPSTSADQQSLYQNADTYVFVGSSRYSKKFKPEIAIRPKVRDQ
EGRMNYYWTLVEPGDKITFEATGNLVVPRYAFAMERNAGSGIIISDTPVHDCNTTCQTPK
GAINTSLPFQNIHPITIGKCPKYVKSTKLRLATGLRNIPSIQSRGLFGAIAGFIEGGWTG
MVDGWYGYHHQNEQGSGYAADLKSTQNAIDEITNKVNSVIEKMNTQFTAVGKEFNHLEKR
IENLNKKVDDGFLDIWTYNAELLVLLENERTLDYHDSNVKNLYEKVRSQLKNNAKEIGNG
CFEFYHKCDNTCMESVKNGTYDYPKYSEEAKLNREEIDGVKLESTRIYQILAIYSTVASS
LVLVVSLGAISFWMCSNGSLQCRICI
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BDBM31148
NameBDBM31148
Synonyms:3-hydroxyquinolin-2(1H)-one, 2 | US9701638, 1
TypeSmall organic molecule
Emp. Form.C9H7NO2
Mol. Mass.161.1574
SMILESOc1cc2ccccc2[nH]c1=O
Structure
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n/a